Xalacom product monograph 4 warnings and precautions general there have been reports of bacterial keratitis associated with the use of multipledose containers of topical ophthalmic products. Prceftriaxone sodium for injection bp sterile ceftriaxone sodium ceftriaxone sodium for injection bp. Voglibose binds to and inhibits alphaglucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. For a complete listing, see the dosage forms, composition and packaging section. Tzd product monograph warnings and precautions information when the use of these drugs in combination with any insulin, including humulinr, humulinn or humulin3070, is contemplated.
Onset of these reactions occurred within the first 3. In addition, the manufacturing process includes two viral inactivationremoval steps. Product monograph prgentamicin injection usp gentamicin base as sulfate usp 10 mgml and 40 mgml antibiotic sandoz canada inc. Voglibose is an alphaglucosidase inhibitor used for lowering. Summary product information route of administration dosage form strength nonmedicinal ingredients oral 500 mcg filmcoated tablet hypromellose, lactose monohydrate, macrogol 4000, magnesium stearate, maize starch, povidone, titanium dioxide and yellow iron oxide indications and clinical use. The drug was approved in japan in 1994 for the treatment of diabetes, and it is. Page 1 of 34 product monograph protezla apremilast tablets 10 mg, 20 mg, and 30 mg selective immunosuppressant celgene inc. Soybean oil, medium chain triglycerides, olive oil and fish oil 6% 6% 5% 3% wv lipid emulsion for intravenous nutrition. Transferring patients from other insulins when patients are transferred between different types of insulin products, including animal. Humira product monograph page 4 of 164 date of revision.
Due to its mechanism of action, patients taking forxiga will test positive for glucose in their urine see drug interactions, druglaboratory. Exchange tower king street west, suite 900 po box 73 toronto, ontario m5x 1b1 18885455972. In general, voglibose has been found to significantly decrease the rapid rise in postprandial glucose. With other members of this class, there have been postmarketing reports of exfoliative skin conditions, including stevensjohnson syndrome. Severe hepatic impairment or endstage liver disease see warnings and precautions. Product monograph starlix nateglinide novartis canada. Women with genital bleeding of unknown etiology or for reasons other than uterine fibroids. Product monograph for nivolumabopdivo for further information on this. Przofran odt oral disintegrating tablets ondansetron. Adrenergic receptor blocking agent laboratoire riva inc.
Warnings and precautions general in the presence of any alarm symptom e. Pr hydrea hydroxyurea capsules usp, 500 mg antineoplastic agent. Patients who are hypersensitive to any of the tricyclic compounds, such as. These containers had been inadvertently contaminated by patients who, in most cases, had a concurrent corneal disease or a disruption of ocular epithelial. Patients with hepatic disease, a history of bonemarrow depression, a history of hepatic. L04aa37 selective immunosuppressant eli lilly canada inc. Please refer to the respective tzd product monograph warnings and precautions information when the use of these drugs in combination with any insulin, including humalog, humalog mix25 and humalog mix50, is contemplated.
Voglibose tablet contains voglibose as an active ingredient. Because clinical trials are conducted under very specific conditions, the adverse reaction rates observed in the clinical trials may not reflect the rates observed in practice and should not be compared to the rates in the clinical trials of another drug. Micardis product monograph page 5 of 33 involvement of tongue, glottis, or larynx, likely to cause airway obstruction, appropriate therapy including, but not limited to 0. Product monograph prrivametoprololl metoprolol tartrate tablets, usp 25 mg, 50 mg and 100 mg. Secondary page of a 20 health canada guidance document. Comparison of acarbose and voglibose in diabetes patients who. Product monograph sterile prceftriaxone sodium for injection bp ceftriaxone as ceftriaxone sodium bp 0. Trelstar may cause fetal harm when administered to a pregnant woman. Voglibose has no inhibitory activity against lactase and so, it does not cause lactose intolerance and diarrhoea. Product monograph prultresa pancrelipase usp capsule delayed release,800, 20,700 and 23,000 usp units of lipase usp pancreatic enzymes a09aa02 aptalis pharma canada inc. History of angioedema with pirfenidone see warnings and precautions. Pr meropenem for inject ion meropenem for injection 500 mg and 1 g vials. General should hypersensitivity develop, discontinue medication and treat the patient symptomatically.
Dec 15, 20 voglibose treatment has resulted in an increased release of glp1, which is an insulinotrupic hormone and it has also increased release of glp1, which is known to enhance insulin secretion and insulin sensitivity. Connaught house, 1st floor 1 burlington road dublin 4 ireland date of preparation. Page 1 of 31 product monograph prcombigan brimonidine tartrate 0. Bexsero is not expected to provide protection against all circulating meningococcal serogroup b strains. Warnings and precautions general as with any vaccine, vaccination with bexsero may not protect all vaccine recipients.
Listing a study does not mean it has been evaluated by the u. Montsainthilaire, quebec canada j3h 6c4 date of approval. For a complete listing of components, see the dosage forms, composition and packaging section of the product monograph. Coadministration with rilpivirine is contraindicated. Patients with severe ketosis or in a state of diabetic coma or. Product monograph komboglyze saxagliptin and metformin hydrochloride tablets as saxagliptin hydrochloride and metformin hydrochloride 2.
Enbrel product monograph page 4 of 89 treatment of adult patients with chronic moderate to severe plaque psoriasis pso who are candidates for systemic therapy or phototherapy. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be. Forms, composition and packaging section of the product monograph. Voglibose delays the absorption of glucose thereby reducing the risk of macrovascular complications. Voglibose should be administered with caution when it is co administered with the following drugs. History of hypersensitivity to voglibose or to any other ingredient of this product. Prrepatha evolocumab solution for subcutaneous injection. These changes have been observed to reverse on discontinuation of therapy. Used as monotherapy as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Longterm administration of trelstar will cause suppression of pituitary gonadotropins and gonadal hormone production with clinical symptoms of hypogonadism. Tzd product monograph warnings and precautions information when the use of these drugs in combination with any insulin, including humulin r, humulin n or humulin 3070, is contemplated. Concomitant use of fluvoxamine see warnings and precautions and drug interactions.
Human glucagon like peptide1 glp1 weight management. Voglibose is a valiolamine derivative and inhibitor of alphaglucosidase with antihyperglycemic activity. Product monograph page 6 of 41 the event, and institute alternative treatment for diabetes see contraindications and adverse reactions. It is important to ensure adequate hydration in patients at all times during therapy with pancreatic enzymes. Dec 26, 20 we studied the efficacy and safety of acarbose in comparison with voglibose in type 2 diabetes patients whose blood glucose levels were inadequately controlled with basal insulin alone or in combination with metformin or a sulfonylurea.
One of the early studies on voglibose efficiency and its effects on digestive enzymes indicated up to 33fold increased inhibition of semipurified porcine small intestine disacchridases than acarbose matsuo et al. Action and clinical pharmacology the precise mechanism of action of tretinoin on the skin is not fully understood. For a complete listing, see the dosage forms, composition and packaging section of the product monograph. Dosage in renal failure voglibose is poorly absorbed after oral doses and renal. The product monograph will be reissued in the event of serious safety concerns previously unidentified or at such time as the sponsor provides the additional data in support of the product s clinical benefit. This study was a 24week prospective, openlabel, randomized, activecontrolled multicenter study. Przofran tablets, oral solution and injection ondansetron hydrochloride dihydrate 4 mg and 8 mg ondansetron hydrochloride dihydrate tablets.
Voglibose is a medicine available in a number of countries worldwide. Voglibose is a research product of takeda pharmaceutical company, japans largest pharmaceutical company. Product monograph prsandoz sertraline sertraline hydrochloride 25 mg, 50 mg and 100 mg capsules as sertraline antidepressant antipanic antiobsessional agent sandoz canada inc. Movantik naloxegol product monograph page 4 of 29 patients with known or suspected gastrointestinal obstruction or in patients at increased risk of recurrent obstruction, due to the potential for gastrointestinal perforation see warnings and precautions, gastrointestinal.
For use during pregnancy and in women who are breastfeeding. Yervoy ipilimumab for injection product monograph page 4 of 53 drug. Women with uterine, cervical, ovarian or breast cancer. In vitro studies indicate that the bactericidal action of ceftriaxone results from the inhibition of cellwall synthesis. Verzenio product monograph page 1of 52 product monograph including patient medication information prverzenio abemaciclibtablets 50 mg, 100 mg, 150 mg, 200 mg protein kinase inhibitor eli lilly canada inc. Product monograph page 5 of 30 a potential increased risk of cardiac failure has also been reported in patients with preexisting cardiovascular disease andor risk factors for cardiovascular disease. Druginduced tumours were not observed in any organ except for the urinary bladder. Product monograph prvolibris ambrisentan tablets 5 mg and 10 mg endothelin receptor antagonist glaxosmithkline inc. Visanne product monograph page 4 of 39 presence or history of severe hepatic disease as long as liver function values have not returned to normal presence or history of liver tumors benign or malignant known or suspected sex hormonedependent malignancies undiagnosed abnormal vaginal bleeding. Voglibose treatment has resulted in an increased release of glp1, which is an insulinotrupic hormone and it has also increased release of glp1, which is known to enhance insulin secretion and insulin sensitivity. Voglibose tablet works by reducing the increase in blood glucose level after meal. Product monograph ritalin methylphenidate hydrochloride 10 mg and 20 mg tablets novartis standard ritalin sr methylphenidate hydrochloride extendedrelease tablets 20 mg tablets novartis standard central nervous system stimulant novartis pharmaceuticals canada inc.
Adalimumab was created using phage display technology resulting in fully human heavy and. If the effect is not sufficient, the quantity of a single dose may be increased up to 0. Results from studies with metformin, pioglitazone thiazolidinedione, voglibose alpha. Trelstar is contraindicated in women who are or may become pregnant while receiving the drug. Platelet transfusion did not reverse the antiplatelet effect of brilinta in healthy volunteers. It is known that tretinoin is both pharmacologically and structurally related to. A product monograph is intended to provide the necessary information for the safe and effective use of a new drug and also to serve as a standard against which. A list of us medications equivalent to voglibose is available on the website. Page 2 of 42 product monograph prnorfloxacin norfloxacin tablets, usp 400 mg therapeutic classification antibacterial agent actions and clinical pharmacology norfloxacin is a quinolone carboxylic acid antibacterial agent for oral administration. Repatha product monograph page 4 of 76 homozygous familial hypercholesterolemia repatha is indicated as an adjunct to diet and other ldllowering therapies e. Patients with concomitant administration of medicinal products that may increase the risk of bleeding, e.
Of the 4204 plaque psoriasis patients exposed to taltz in clinical trials, a total of 301 were 65. Actos product monograph page 5 of 45 approximately 14 times the maximum recommended human oral dose of 45 mg based on mgm 2. Ravicti product monograph page 1 of 28 product monograph including patient medication information pr ravictitm glycerol phenylbutyrate oral liquid 1. Trademarks are owned by or licensed to the gsk group of companies.
1346 368 425 824 701 1592 1551 87 1390 1358 1573 1613 562 1514 822 1506 1471 342 286 557 556 1026 1637 257 1047 758 1177 715 400 344 772 439 588 484 1375 1295 14 53 992 1336 314